A mating-type-specific sterility genemaplis required for transcription of a mating-type genemat1-Pi in the fission yeastSchizosaccharomyces pombe

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Mating-type Mutations in Schzzosaccharomyces Pombe:

Mutants defective in various steps of the sexual cycle have been isolated from homothallic strains of Schizosaccharomyces pombe by BRESCH, MULLER and EGEL (1968). These mutants include heterothallic h+ and hstrains. We have isolated additional h+ and hmutants from homothallic strains. Those mutants which are due to mutations in the mating-type region were analyzed in detail. Our results show th...

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Silent Mating-Type Loci in Fission Yeast

In Schizosaccharomyces Pombe the mating-type information is stored at two transcriptionally silent loci (mat2 and mat3). The region between these sites ( K region) is inert for meiotic crossing over. The mating-type genes (M or P) are expressed only when present at a third, active locus (matl). We have earlier shown that the positional regulation of P genes is based on repression at the silent ...

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Genes required for initiation and resolution steps of mating-type switching in fission yeast.

The fission yeast Schizosaccharomyces pombe switches mating type by transposition of a copy of DNA derived from either of the two storage cassettes, mat2 -P and mat3 -M, into the expression locus, mat1 . The recombinational event of switching is initiated by a double-stranded DNA break present in approximately 20% of the molecules at mat1 . Fifty-three mutants defective in switching of mating t...

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ژورنال

عنوان ژورنال: FEMS Microbiology Letters

سال: 1989

ISSN: 0378-1097,1574-6968

DOI: 10.1111/j.1574-6968.1989.tb03417.x